Celecoxib-induced cholestatic liver injury

Abstract

Although drug-induced liver injury is common, physician awareness of specific drug reactions is often limited. Celecoxib-induced drug injury has not been widely reported. We describe the case of a 28 year-old woman who presented to the emergency department with cholestatic liver injury following 13 days of celecoxib use. We searched the literature and reviewed existing case reports of celecoxib-induced liver injury to highlight similarities and offer a discussion of the associated pathology.