Effects of Shang Ke Jie Gu tablet on fracture healing in rabbits

Yanhua Ma, Fuyan Xie, Wa Gao


Objective: To study the effects of Shang Ke Jie Gu tablet on fracture healing in rabbits.

Methods: 40 New Zealand rabbits, half male and half female, were randomly divided into two groups: normal saline group (N group) and Shang Ke Jie Gu tablet group (S group). Each group consisted of 20 rabbits. Left radial fracture models in upper and middle sections were made in rabbits and then intra-gastric administration was given. Five rabbits in each group were killed on the 10th, 20th, 30th and 40th day after surgery, left radius was taken to get an X-ray. The degree of healing was assessed by the evaluation criteria of Shanghai Orthopaedics Institute.

Results: The degree of fracture healing in S group was higher in the comparison with that in N group.

Conclusions: Shang Ke Jie Gu tablet might affect endochondral ossification during fracture healing of rabbits, and promote porosis and fracture healing.

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DOI: https://doi.org/10.5430/dcc.v3n3p6


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