Experimental study of the effects of Ulinastatin on reducing MDA in free flaps

Abstract

Free flap transplantation is the most important plastic surgery treatment. Although free flap is an important tissue repair tool for plastic surgery, it is easy to happen due to the anastomotic stenosis or thrombosis, as well as the inflammatory reaction caused by ischemia-reperfusion injury of the flap and the inflammation caused by these inflammatory reactions. Microcirculation contracture or occlusion will lead to partial or complete flap necrosis, thus affecting the repair effect. Numerous studies show that neutrophils are closely involved in the process of ischemic injury of free flaps. The purpose of this experiment is to investigate the use of ulinastatin to inhibit the inflammatory infiltration of free flaps to improve the survival of the flap.