Recurrence of a de-differentiated liposarcoma of the colon

Mairead M. Hennessy, John E. O’Connell, David E. Kearney, Emmet J. Andrews


We present the case of a 56-year-old gentleman who presented with non specific malaise, myalgia and anorexia. Clinical examination revealed a large circumscribed palpable mass in the left iliac fossa. He underwent an intraabdominal pelvic biopsy, computed tomography (CT), magnetic resonance imaging (MRI) of abdominal wall and Positron Emmission Tomography (PET). Differential diagnoses included Gastro Intestinal Stromal Tumour (GIST) and sarcoma. He underwent a laparotomy and excision of the lesion. Histological analysis of the lesion demonstrated a dedifferentiated liposarcoma involving the colon and adjacent pericolic fat. Margins were clear and there was no nodal involvement. He declined adjuvant chemotherapy. He subsequently developed a local recurrence, which was deemed unresectable. He commenced chemotherapy but continued to deteriorate. He received palliative treatment and died 6 months following his initial surgery.

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Case Reports in Clinical Pathology

ISSN 2331-2726(Print)  ISSN 2331-2734(Online)

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