Small cell lung carcinoma in a patient with previously diagnosed Ménétrier’s disease: Is this another neuroendocrine manifestation of the neoplastic potential of this condition?

Eleanor Gerada, Jurgen Gerada, Lianne Camilleri, Darko Babic, Josef Micallef


A 73-year old man with a history of Ménétrier’s disease developed a mass in the axilla. Histology revealed this to be a metastatic neuroendocrine carcinoma, most consistent with a lung primary. Computed tomography scan of the thorax showed a 28mm lesion in close proximity to the right bronchus intermedius. Cytological specimen from bronchoalveolar lavage yielded small cell carcinoma cells. Serum chromogranin A and serum gastrin levels were found to be significantly elevated. Ménétrier’s disease has been associated with malignancy especially neuroendocrine neoplasms. Small cell lung carcinoma is also a high grade neuroendocrine lung neoplasm. In this report we will bring forward hypotheses about possible links between the two conditions.


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Case Reports in Internal Medicine

ISSN 2332-7243(Print)  ISSN 2332-7251(Online)

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