Glibenclamide (glyburide) delay electrocardiographic ST-segment elevation in a diabetic patient with acute myocardial infarction

Ying-Chih Chen, Po-Chao Hsu, Chun-Yuan Chu, Wen-Hsien Lee, Ho-Ming Su, Tsung-Hsien Lin, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu


Acute myocardial infarction (AMI) is the most frequent cause of death worldwide. The timely diagnosis of AMI, especially ST-segment elevation myocardial infarction, is a key to successful management. A 12-lead electrocardiography (ECG) should be obtained and interpreted as soon as possible. The 12 lead ECG diagnosis may be more difficult in patients without diagnostic ST-segment elevation but with persistent typical ischemic symptoms. Here, we present a diabetic patient with AMI where the ST-segment elevation was masked by glibenclamide (glyburide) initially and delayed ECG change was revealed after glibenclamide was eliminated.

Full Text:




  • There are currently no refbacks.

Case Reports in Internal Medicine

ISSN 2332-7243(Print)  ISSN 2332-7251(Online)

Copyright © Sciedu Press

To make sure that you can receive messages from us, please add the ‘’ domains to your e-mail 'safe list'. If you do not receive e-mail in your 'inbox', please check your 'spam' or 'junk' folder.