A clinical dilemma: malignant adenomyoepithelioma of the breast – case report and review of literature

Ahmad SS, Hassan M, Alam S, Aftab F


Malignant myoepithelioma of the breast is a rare lesion characterized by the malignant proliferation of the epithelial and myoepithelial cells that exhibit characteristic histological and immuno- histochemical features. Very few cases have been reported in literature. We report a case of a 64-year-old female with a palpable lump in the upper outer quadrant of her right breast, present for a number of years. She underwent lumpectomy under local anesthesia. Upon histological confirmation of the diagnosis of malignant myoepithelioma, the patient underwent wide local excision with sentinel node mapping. Malignancy was evident by extensive central infarction. The tumour was completely triple negative, i.e. Estrogen receptor (ER), Progesterone receptor (PR) and Human epidermal growth factor receptor 2 (HER2) negative. The patient also underwent adjuvant chemotherapy and radiation therapy. The patient remains well with no recurrence 7 years since her initial surgery. The authors believe, that due to the paucity of these rare tumours, optimal treatment strategies remain to be determined.

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DOI: https://doi.org/10.5430/css.v2n1p64


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Case Studies in Surgery  ISSN 2377-7311(Print)  ISSN 2377-732X(Online)

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