Late pulmonary metastasis of inflammatory breast cancer 26 years after initial radiation therapy alone

Kun-Ming Wu, Chih-Hao Chen, Ho Chang, Chao-Hung Chen


A 64-year-old woman underwent cobalt-60 radiation therapy 26 years ago because of advanced inflammatory breast cancer. The initial stage was T4N0M0. During the course of cobalt-60 therapy, the patient presented severe chest wall necrosis. Her chest wall wound healed very slowly and she decided to stop radiation therapy and declined both surgery as well as chemotherapy. After chronic wound healing, the patient did not come back for follow-up. Twenty-six years later, she came back for mild dyspnea. Subsequent study showed suspicious lung metastasis. Later, she underwent thoracoscopic biopsy, with which lung metastasis was confirmed. She recovered well and currently receives oral chemotherapy for disease control.

Full Text:



Pacelli, R., et al., Radiation therapy following surgery for localized breast cancer: outcome prediction by classical prognostic factors and approximatedgenetic subtypes. J Radiat Res, 2013. 54(2): p. 292-8.

Yang, T.J. and A.Y. Ho, Radiation therapy in the management of breast cancer. Surg Clin North Am, 2013. 93(2): p. 455-71.

Hequet, D., et al., Systematic cavity shaving: Modifications of breast cancer management and long-term local recurrence, a multicentre study. Eur J Surg Oncol, 2013. 39(8): p. 899-905.

van der Sangen, M.J., et al., Detection of local recurrence following breast-conserving treatment in young women with early breast cancer: optimization of long-term follow-up strategies. Breast, 2013. 22(3): p. 351-6.



  • There are currently no refbacks.

Case Studies in Surgery  ISSN 2377-7311(Print)  ISSN 2377-732X(Online)

Copyright © Sciedu Press

To make sure that you can receive messages from us, please add the '' and ‘’ domains to your e-mail 'safe list'. If you do not receive e-mail in your 'inbox', please check your 'spam' or 'junk' folder.